Indivumed Joins KHR Biotech

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Expanding Partnership with University Medical Center Mainz

Indivumed GmbH (“Indivumed”) CEO Dr. Hartmut Juhl and University Medical Center Mainz Professor Krishnaraj Rajalingam today announced Indivumed will be joining the newly formed KHR Biotech GmbH (“KHR Biotech”) – a spin-off biopharma company from University Mainz. KHR Biotech will develop cancer therapeutics for colorectal cancer that efficiently inhibit oncogenic signaling pathways based on patents secured through Prof. Rajalingam’s research on RAS pathway mutations.

New Entity to Develop Therapeutics Targeting RAS Pathway Mutations in Colorectal Cancer (Picture: © Indivumed GmbH)
New Entity to Develop Therapeutics Targeting RAS Pathway Mutations in Colorectal Cancer (Picture: © Indivumed GmbH)
Indivumed Joins KHR Biotech

The new company will combine Prof. Rajalingam’s research and scientific approach with Indivumed’s database and AI capabilities in order to bring new compounds targeting pertinent oncogenic signaling pathways into the clinical phase. “Supported by the tremendous amount of data and analytical tools that the IndivuType discovery solution provides, we are able to continue our rapid expansion into cancer drug development,” said Prof. Dr. Hartmut Juhl, CEO and Founder of Indivumed. “As a part of KHR Biotech, we are proud to be working with University Medical Center Mainz and Dr. Rajalingam, one of the brightest minds in cancer research, to better understand and to develop treatments for RAS pathway mutations in cancer.”

“Supported by the tremendous amount of data and analytical tools that the IndivuType discovery solution provides, we are able to continue our rapid expansion into cancer drug development."

– Prof. Dr. Hartmut Juhl, CEO and Founder of Indivumed

One of the leading molecular biologists working on drug development and the RAS pathway, Prof. Rajalingam will serve as Managing Director of KHR Biotech. KHR Biotech’s approach to drug development is based on several years of both publically and privately funded research conducted by Prof. Rajalingam and the University Medical Center Mainz. Indivumed has been a long-term partner of the research project, originally by providing tissue samples and lab testing and more recently by validating approaches and targets using its cancer database solution, IndivuType.

“It is truly rewarding to know that longstanding research on oncogenic signaling pathways can now be used to advance the development of cancer therapeutics for the benefit of previously unmet medical needs,” said Prof. Krishnaraj Rajalingam. “The IndivuType discovery solution offers tremendous promise in the effort to develop new therapeutic tools in the fight against cancer. I look forward to working with Prof. Juhl and the Indivumed team in their effort to individualize the diagnosis and treatment of cancer.”

The founding of KHR Biotech follows the recent announcement of Indivumed’s official expansion into target discovery and early cancer drug development. KHR Biotech will leverage advanced AI analytics and comprehensive clinical data from thousands of samples obtained under identical, highly standardized conditions from each patient contained within IndivuType, Indivumed’s multi-omics discovery solution.

University Medical Center Mainz Scientific Board Director Prof. Dr. Ulrich Foerstermann added, “With the formation of KHR Biotech, an important step has been taken in the translation of successful basic research towards practical application on patients which is the prime goal of our Research Center for Translational Medicine at UMC Mainz.”

As the company prepares for transition into the clinical phase, KHR Biotech plans to announce first clinical results in 2022.

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